PPP3CA-DT and colorectal carcinoma: SRSP interacts with splicing factor serine‐ and arginine‐rich splicing factor 3 (SRSF3) to increase the binding of SRSF3 to exon 3 of transcription factor Sp4 and resulted in the inclusion of exon 3, thereby inducing formation of the long Sp4 isoform (L‐Sp4 protein) and suppressing formation of the short Sp4 isoform (S‐Sp4 peptide) which has no transactivation domain to promote CRC tumorigenesis and progression.