BCL2 and non-small cell lung carcinoma: Similar to our findings, apoptosis-inhibited molecules (Bcl-2) were apparently lowered, but pro-apoptotic factors including Bax and Caspase-3 were greatly elevated in treated NSCLC rats with anti-miR-22, indicating that inhibition of miR-22 may promote apoptosis to increase the therapeutic outcomes and suppress the tumor growth.