Also Fraga et al. 28 reported no independent role for CD57 cell density in the tumor with survival although they found significant associations between high CD57+ inflammatory cell density with tumor size and more locoregional metastases; they concluded that a higher density of such cells the peritumoral stroma might lead to an ineffective locoregional antitumoral response28. The gene discussed is B3GAT1; the disease is neoplasm.