As a central regulator of cell growth and size, it is not surprising that the Hippo pathway is involved in a number of tumour types, including NF2-associated tumours.68 The NF2 disease, characterised by highly penetrant tumours of the vestibular nerve called vestibular schwannomas, is caused by biallelic inactivation of the NF2 gene. Here, NF2 is linked to neoplasm.