Other studies detected the effect of flavopiridol on glycolytic signaling pathway and observed that glucose metabolism-related enzymes, such as GLUT1, 3, and 4, hexokinase II, pyruvate kinase, and glycogen phosphorylase, which are known to be upregulated in glioblastoma cells, were significantly downregulated upon flavopiridol treatment45. The gene discussed is SLC2A1; the disease is glioblastoma.