Hypothesizing that BCR-ABL1T315I+ leukemia cells deposit less fibronectin than BCR-ABL1+ leukemia cells due to differences in signaling pathways, we focused on ILK, a pseudokinase belonging to the family of RAF-like kinases involved in integrin-mediated signal transduction [37] and fibronectin deposition [38, 39]. The gene discussed is BCR; the disease is leukemia.