Human TRM cells infiltrating the lungs express CXCR3, CXCR6 and CCR6 at higher levels compared to blood TEM cells31, while in our macaque tumour model, CXCR3 but not CXCR6 or CCR6 was upregulated in CD8+ TILs. Here, CXCR6 is linked to neoplasm.