CD4 and HIV infectious disease: For instance, topic M31 is enriched for alcoholic cirrhosis billing codes and ascites-based lab tests typical for cirrhosis patients; in M42, the code for HIV infection is grouped with abnormal counts of immune cells, including CD4 lymphocytes; diabetes codes tend to rank highly alongside high blood acetone in M48, and topic M62 is enriched for opioid abuse along with valproic acid and lithium prescriptions—common treatments for bipolar disorder.