When TAM-treated Krt5-CreERT2;TdtLSL mice (n = 4) were induced to form cancer with OHBBN and subsequently assessed for Epcam-CD49f expression we observed significant distribution of tomato positive cells to all gates (G1 = 31.4%, G2 = 39.5%, G3 = 20.5%, G4 = 6.9%, n = 4) (Fig. 7a, bottom). The gene discussed is KRT5; the disease is cancer.