EPHX2 and liver dysplastic nodule: Given the potential role of sEH inhibition in DN, the aim of this study was to evaluate the effects of the sEH inhibitor t-AUCB on proximal tubular injury in the kidneys of db/db mice and clarify the possible mechanisms underlying the regulation of mitochondrial dysfunction, ER stress and autophagy flux by t-AUCB in HK-2 cells exposed to HG conditions.