To explore the correlation between APE1, GFRα1, and pancreatic cancer progression, immunohistochemical analyses of APE1 and GFRα1 expression were performed utilizing primary tissues of 37 pancreatic adenocarcinoma patients, and its clinicopathological parameters are shown in Table 1 based on different grades and stages. Here, APEX1 is linked to familial pancreatic carcinoma.