In spite of EpCAM expression close to 100% of tumor cells, JAR lysis triggered by the EpCAM/CD3-bAb reaches only 25.9 ± 1.6% at 1 μg/mL and 21.2 ± 3.3% at 0.1 μg/mL bAb. The gene discussed is EPCAM; the disease is neoplasm.