The top ten KEGG pathways that had the most significant enrichment terms were Toll-like receptor signaling pathway, TNF signaling pathway, PI3K/Akt signaling pathway, pathway in cancer, HIF-1 signaling pathway, Epstein–Barr virus infection, ECM–receptor interaction, cytokine–cytokine receptor interaction, Chagas disease (American trypanosomiasis) and cell cycle. Here, TNF is linked to American trypanosomiasis.