One of the most interesting findings in this study was that NF‐κB can also regulate the expression of SNHG16. While SNHG16 has been identified as an oncogene in many cancers including HCC,28, 29, 30, 31, 32, 33, 34 the biological functions of SNHG16 and its underlying mechanisms in HCC are not fully understood. The gene discussed is NFKB1; the disease is cancer.