Intravenous thrombolysis (IVT) with recombinant tissue plasminogen activator (r‐tPA) is an effective treatment for acute ischemic stroke (AIS) patients when administered within 4.5 hr of stroke onset (Hacke et al., 2008; The National Institute of Neurological Disorders & Stroke RT‐PA Stroke Study Group, 1995). The gene discussed is PLAT; the disease is Stroke.