LYST and steatosis: Lysosomal trafficking regulator (LYST) is the transport protein implicated in Chédiak-Higashi disease, and the lystmuz107/muz107 (Table 2 and Supplementary Table S1) zebrafish was isolated from a forward genetic screen for inherited liver disease, which identified hepatic steatosis and hepatomegaly in a zebrafish mutant that contained a point mutation in the lyst locus (Kim et al., 2015).