Of the 17 known GSDs (Sara and Alan, 2018), Pompe disease (GSD II) and Danon disease (also classifiable as an integral membrane protein disorder) are categorized as LSDs given their involvement of the lysosomal acid α-glucosidase (GAA) and LAMP2, respectively (Platt et al., 2018). The gene discussed is GAA; the disease is glycogen storage disease II.