ADAM10 and cancer: ADAM10 is a cell surface enzyme that sheds a wide variety of cell surface proteins (Dreymueller et al., 2015; Kuhn et al., 2016; Camodeca et al., 2019; Scharfenberg et al., 2019) with importance in the progression of cancer, inflammation and immune response, suggesting that ADAM10 can be an important target for therapy.