In another study the RNA extracted from CSF of a cohort of 27 PD patients and 30 controls was analyzed by RNA-seq: among the differentially expressed transcripts, the lncRNA SCN9 antisense (AC010127.3) and two lncRNAs close to LRRK2 locus (AC079630 and UC001lva.4) have been suggested as potential RNA biomarkers for diagnosis and response to treatment of PD (Hossein-Nezhad et al., 2016). This evidence concerns the gene CLPB and Parkinson disease.