There were no significant differences between cases and controls in the majority of comparisons (Tables 2, 3, 4, P > 0.05), indicating that XPA rs1800975 does not seem to contribute to the risk of specific cancer types, such as breast cancer, esophageal cancer, gastric cancer, reproductive system cancer, endometrial cancer, or head and neck cancer. The gene discussed is XPA; the disease is head and neck cancer.