For example, CRNDE could accelerated non-small-cell lung cancer (NSCLC) progression by sponging miR-338-3p [25] and enhanced HCC carcinogenesis by sponging miR-203, miR-384 or miR-217, thereby mediating BCAT1, NF-κB, p-AKT and MAPK1 expression [22, 24, 38]. The gene discussed is AKT1; the disease is non-small cell lung carcinoma.