CD79A and HIV infectious disease: First, in the absence of HIV infection, ATB individuals exhibited higher levels of IgG and IgA subclass titers to PPD, Ag85, and ESAT6/CFP10 than LTBI individuals (Fig. 3A, C, and D; Fig. S1 and S2), consistent with previous work describing higher M. tuberculosis-specific antibody titers in active disease (32, 45, –, 47).