However, ATB/HIV+ individuals did exhibit significantly reduced IgG2, IgG4, IgA1, IgA2, and IgM titers to tetanus toxoid (Fig. S1 and S2), as well as reduced IgG1, IgG2, and IgM titers to influenza HA compared with ATB/HIV− individuals (Fig. S1 and S2). The gene discussed is CD40LG; the disease is influenza.