In the comparison among the treatment groups, AD+40+EX was significantly different from AD+40 (Bax, Bcl-2, cytochrome C, cleaved caspase-3, P < .001 each) and AD+EX exposure (Bax, Bcl-2, cytochrome c, cleaved caspase-3, P < .001 each), while AD+40 and AD+EX did not show an intergroup difference. Here, BCL2 is linked to Alzheimer disease.