The chemokines CXCL1 and CXCL6 are chemotactic cytokines involved in various pathological processes including inflammatory diseases, and it has been shown that both CXCL1, CXCL6, and SEMA7A are involved in the inflammatory response in joint-related diseases such as rheumatoid arthritis [28, 29]. The gene discussed is CXCL6; the disease is rheumatoid arthritis.