Such TCR beta-chain sequences were identified for T1D (proinsulin, ZNT8, GAD65, and islet autoreactive TCRs) (Culina et al., 2018, Gomez-Tourino et al., 2017), Hashimoto’s thyroiditis (thyroglobulin) (Matsuoka et al., 1994), and vitiligo (PMEL, MART1) (Lang et al., 2001, Zarour et al., 1996). This evidence concerns the gene GAD2 and type 1 diabetes mellitus.