CD4 and neoplasm: Univariate analysis revealed a significant association between stromal PD-1+ immune cell infiltration, stromal CD3+ immune cell infiltration, stromal CD4+ immune cell infiltration, combined tumour and stromal infiltration of CD8+ immune cells, combined intermediate-to-high stromal infiltration of CD8+ and PD-1+ immune cells and combined stromal infiltration by PD-L1+ and CD8+ immune cells and DCB (Table 2).