At the transcript level, the expression of the full-length CNR1 transcript (Fig. 2) was downregulated significantly in the DLPFC of patients with schizophrenia (p = 8.86E−03, FDR = 0.02), and patients with MDD (p = 1.18E−04, FDR = 7.50E−04), but not in patients with bipolar disorder (p = 0.40). The gene discussed is CNR1; the disease is major depressive disorder.