To assess the impact of CD103 on the regulation of the axis of IL-22-IL-23-IL-17 cytokine, we compared the induction of IL-17A- and IL-22-producing lymphocytes in the skin-draining PLNs between WT mice and Cd103−/− mice following initiation of psoriasiform dermatitis. The gene discussed is IL23A; the disease is Psoriasiform dermatitis.