In our study, 2 weeks after transgene excision, Vhlf/f‐deficient mice showed mild to moderate NASH features with a median NAFLD activity score of 4.5, similar findings to that reported by Qu et al13 In particular, these authors observed that livers of mice overexpressing HIFs after 2 weeks of disrupting the Vhl gene in hepatocytes displayed NASH features along with a marked increase of Cd36 mRNA levels. This evidence concerns the gene CD36 and metabolic dysfunction-associated steatohepatitis.