Noteworthy, experimental studies have demonstrated that CD36 plays a key role in the hepatosteatosis setup in rodents 20, 21 and, more interestingly, NAFLD patients present high hepatic CD36 mRNA levels,22 and this FFA transporter is largely overexpressed in the plasma membrane of hepatocytes.23 This evidence concerns the gene CD36 and metabolic dysfunction-associated steatotic liver disease.