Rotor syndrome is another disease characterized by a benign increase in conjugated bilirubin, caused by simultaneous mutations in two members of the OATP family (OATP1B1, gene SLCO1A2 and OATP1B3, gene SLCO1B3) located on the hepatocyte sinusoidal membrane which serve to reabsorb conjugated bilirubin (31). Here, SLCO1B3 is linked to Rotor syndrome.