MGMT and astrocytoma (excluding glioblastoma): A study confirmed that Ktrans is related to the O6-methylguanine-DNA methyltransferase (MGMT) methylation status of glioblastomas (14) and relative CBV (rCBV) can predict the isocitrate dehydrogenase 1 (IDH1) mutation statuses in astrocytomas (15).