Searching for our mutated genes in the large pediatric cancer databases PECAN and PedcBioPortal (any tumor) revealed CTNNB1 as the most commonly mutated gene, followed by DEPDC5 (several variants were identified in 12 types of pediatric tumors) in PECAN, and FRMPD1 in PedcBioPortal. This evidence concerns the gene CTNNB1 and cancer.