Changes in physiology, diabetes factors, and neutrophil functions associated with changes in IL-8 and IL-15 suggest positive correlations with changes in rVO2peak and IL-15 (Figure 3J: r = 0.781, p = 0.008), fasting insulin and IL-15 (Figure 3K: r = 0.661, p = 0.038), and non-significant positive trends between fasting insulin and IL-8 (Figure 3L: r = 0.579, p = 0.08), phagocytosis and IL-8 (Figure 3M: r = 0.650, p = 0.058) and chemotaxis and IL-15 (Figure 3N: r = 0.598, p = 0.068). The gene discussed is CXCL8; the disease is diabetes mellitus.