At last, we compared the difference of T-bet expression between Lck-mTOR mice and Lck-TSC1 mice under the same infection degree (MSS group) and found that in the same MSS group (Figure 4E), Lck-mTOR mice had more T-bet expression than WT mice, while Lck-TSC1 mice had less expression than WT mice. This evidence concerns the gene TSC1 and infection.