LGI1 and encephalitis: The AE mediated by these antibodies accounted for 10–20% of all types of encephalitis, and the most common subtype among them is anti-NMDAR encephalitis, which accounts for ~80% of AE, followed by LGI1 antibody-associated encephalitis (LGI1 AE) and anti-GABABR encephalitis (2).