Even though SIRT1 has been found as a potential target of miRNA-138 in macrophages, smooth muscle cells, endothelial cells, and tumor cells, no data has been published in PCa concerning miR-138 and SIRT1 expression (Xu et al., 2015; Zhu et al., 2017; Bai et al., 2018). The gene discussed is SIRT1; the disease is posterior cortical atrophy.