Various studies indicated that some miRNAs related with SIRT1, such as miR-204, miE-212/132, miR-449a, miR-221/222, and miR-34a, induce cell growth, invasion, and angiogensis in PCa (Karbasforooshan et al., 2018; Kasomva et al., 2018). This evidence concerns the gene SIRT1 and posterior cortical atrophy.