Therefore, in order to further understand the regulatory mechanism of ABCA8 as it relates to HCC, we identified miRNAs that could be upstream regulators of ABCA8 through the publicly accessible databases, TargetScan (http://www.targetscan.org/vert_72/), miRDB (http://mirdb.org/) and miTarBase (http://mirtarbase.mbc.nctu.edu.tw/php/index.php). The gene discussed is ABCA8; the disease is hepatocellular carcinoma.