This region contains critical oncogenes involved in tumor progression, such as MET proto-oncogene receptor tyrosine kinase (MET), hepatocyte growth factor (HGF), SEM1 26S proteasome complex subunit (SHFM1), minichromosome maintenance complex component 7 (MCM7), and ATP binding cassette subfamily B member 4 (ABCB4, 12]. The gene discussed is SEM1; the disease is neoplasm.