ESR1 and neoplasm: In the multivariate analysis, when adjusted to tumor size, LN metastasis, and SBR grade (other significant prognostic factors in the univariate model), high ERα-36 expression was still an independent predictor of poorer DMFS (HR = 1.93, 95%CI 1.1–3.3, p = 0.016) with a tendency towards poorer OS (HR = 1.65, 95%CI 0.9–3.0, p = 0.09).