Compared to being treated only with non-insulin anti-DM drugs not at risk for hypoglycaemia, all other treatment modalities were strongly associated with a lower probability of not being susceptible to ED attendances for hypoglycaemia (OR = 0.01, 95% CI = 0.00–0.02 for insulin alone to OR = 0.09, 95% CI = 0.04–0.19 for other anti-DM drugs at risk for hypoglycaemia); while, no statistically significant effect was seen for event rate. The gene discussed is INS; the disease is diabetes mellitus.