This was evidenced by less severe symptoms, higher systemic resistance such as modulation of photosynthesis, antioxidant machinery, osmolyte biosynthesis and the expression of stress-related genes such as PR1 and PAL1. The mechanism of GB and CHT effect is to enhance the plant defense against virus infection by increasing the content of SA and JA hormones which produced by the pathway of some enzymes such as PAL and LOX. This evidence concerns the gene TMEM37 and viral infectious disease.