On the other hand, in a study conducted by Rossini et al. [74], the authors found that patients with mastocytosis had elevated serum DKK1 levels when compared with controls, which correlated positively with CTX levels and increased bone resorption, while Rabenhorst highlighted elevated sclerostin levels in patients with mastocytosis and bone disease [75]. This evidence concerns the gene SOST and mastocytosis.