Because a high level of ROS results in higher transcription and translation of the SOD1 gene [41], we might speculate that an increased ROS level, constantly perpetuated along the athlete’s career, will induce an almost constant SOD1 overexpression and thus promote the concentration-dependent formation of SOD1-amyloid-like aggregates [42] possibly associated with the pathogenesis of this neurodegenerative disease. Here, SOD1 is linked to neurodegenerative disease.