As the technology of next generation sequencing grows expeditiously, causative genetic variants of DCM have been detected in over 30 genes, with a great number of them encoding sarcomere proteins, such as TTN, MYH6, MYH7, and TNNT2, and others encoding proteins constituting calcium or potassium channels, such as SCN5A, proteins essential in the nuclear membrane, such as LMNA, as well as others such as BAG3 or TAZ (G 4.5) [1,5]. The gene discussed is TTN; the disease is familial dilated cardiomyopathy.