The overexpression of oncogenic proteins, such as Cyclin-D1, MCL-1, C-FLIP, XIAP, MMP-9, MMP-2, uPA, and VEGF, are correlated with constitutive NF-κB activity and involved in promoting tumor progression in CRC [26,27,28,29]. This evidence concerns the gene NFKB1 and colorectal carcinoma.