EMT markers (Snai1, Snai2, Twist1, Zeb1, and Zeb2), epithelial markers (Cdh1, Egfr, Epcam, Krt7, Krt8, Krt18, and Krt19) [23], mesenchymal markers (Cdh2, Fn1, Itga5, Sdc1, S100a4, and Vim) [20,23], pancreatic cancer stemness markers (Abcg2, Aldh1a1, Aldh1a2, Cd24a, Cd44, Cxcr4, Met, Prom1, Klf4, Nanog and Sox2) [30,31], and a proliferation marker (Mki67) were included to plot the heatmap (Figure 3A). This evidence concerns the gene S100A4 and familial pancreatic carcinoma.