FAM193B and Alzheimer disease: SNPs with 5E-08 ≤ PGWAS < 5E-06 were found within ±1 Mb flanking regions of probes corresponding to FAM193B, BPGM, ZNF598, and C16orf80. Moreover, empirical evidence links some of these genes to AD in humans and animal models (e.g., SLC6A7 [72] and BPGM [71]).