ABCB1 and Familial prostate cancer: High levels of ABCB1 expression have been found in many different cancers, including thyroid, lung, and breast cancer, chronic myeloid leukemia, ependymoma, and osteosarcoma [10–15]; inhibiting ABCB1 expression reverses docetaxel resistance in prostate cancer [16], as well as paclitaxel and olaparib resistance in ovarian cancer cells [17].