NOX1 and malignant colon neoplasm: Indeed, we demonstrate in these experiments that the immunoreactivity of our NOX1 mAb correlated very well with PMA-mediated ROS production as measured by luminescence assay; we also demonstrate that the long form of NOX1, NOX1-L, is the predominant form of NOX1 that contributes to superoxide production in colon cancer cell lines.