Both CDH6 (β = 0.624, P = 5.52 × 10−4, FDR = 0.030) and HAGH (β = 0.491, P = 6.62 × 10−4, FDR = 0.030) proteins remained significantly associated with AD even after adjusting for other covariates in model 2 (Supplementary Table 1). The gene discussed is CDH6; the disease is Alzheimer disease.