The following potential proteases for the different CKD aetiologies were identified: ADPKD (MMP7), MCD (CTSB, CTSD, CTSE, MEP1A, MMP7, PGA3), MGN (MMP3, MMP7, MMP9, MMP13, MMP14), IgAN (MMP7), FSGS (MMP3, MMP7), vasculitis (PGA3), nephritis (MMP7, MMP9), nephrosclerosis (MMP7), and DKD (MMP9). Here, MMP3 is linked to nephritis.